Preventive Health
Advanced technology
[PDF]Ultrasound-Guided PRP and SVF Therapy for Severe Knee Osteoarthritis
This study demonstrates the significant and sustained improvement in clinical symptoms of severe knee osteoarthritis patients treated with ultrasound-guided platelet-rich plasma (PRP) and stromal vascular fraction (SVF) therapy, as measured by WOMAC and VAS scores over a 12-month period.
[PDF]Management of Knee Osteoarthritis
This case series involves four knee osteoarthritis patients treated with autologous StroMed cell injections, platelet-rich plasma (PRP), and exercise rehabilitation. The therapy significantly improved pain, quality of life, and mobility, as measured by KOOS and physical function tests. This combined approach may benefit osteoarthritis patients without pharmaceutical options to slow disease progression.
Lipofilling, utilizing adipose-derived stem cells (ADSCs) from the stromal vascular fraction (SVF), is effective for scar treatment. A review of 19 out of 514 studies showed beneficial outcomes for 665 patients, with six studies indicating noninferiority to platelet-rich plasma or CO2 fractional laser.
[PDF]Stromal Vascular Fraction on Wound Healing
This study compared SVF isolated by ultrasonic (U-SVF) and enzymatic (E-SVF) methods. Both showed similar stem cell characteristics, but U-SVF had more and smaller exosome particles. Both methods demonstrated good trilineage differentiation. SVF exosomes improved fibroblast migration and gene expression, suggesting a new strategy for soft tissue repair.
[PDF]Extracellular vesicles (EVs)
Extracellular vesicles (EVs), including exosomes and microvesicles, are cell-derived structures involved in hair follicle cycle and stem cell function. Investigating EVs' role in skin homeostasis and hair cycling could aid in developing treatments for various skin disorders.
[PDF]Evaluating Mesenchymal Stem Cell Therapy for Osteoarthritis: A Systematic Review
Osteoarthritis (OA) is a leading cause of disability in the world. Mesenchymal stem cells (MSCs) have been studied to treat OA. This review was performed to systematically assess the quality of literature and compare the procedural specifics surrounding MSC therapy for osteoarthritis.
